Description of Zepbound
- Active Ingredient: Tirzepatide.
- Drug Class: It is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist. It works by reducing appetite and slowing down the movement of food through the body, which helps you feel fuller longer and consume fewer calories.
- Indication: It is used as an adjunct to a reduced-calorie diet and increased physical activity for:
- Chronic weight management in adults with obesity or those who are overweight and have at least one weight-related comorbid condition (e.g., high blood pressure, type 2 diabetes).
- Treatment of moderate-to-severe obstructive sleep apnea (OSA) in adults with obesity.
- Form and Administration: Zepbound comes as a liquid solution in a prefilled, single-dose, disposable injection pen or a single-dose vial. It is administered as a subcutaneous injection once weekly into the abdomen, thigh, or upper arm.
- Dosage: The strength is the initial recommended starting dosage, typically injected once weekly for the first four weeks of treatment. This low dose helps the body adjust to the medication and reduces the risk of gastrointestinal side effects. It is not approved as a maintenance dosage. The dose is then gradually increased based on a healthcare provider’s recommendation.
- Common Side Effects: The most common side effects include nausea, diarrhea, constipation, vomiting, abdominal pain, and injection site reactions.

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